Result: High content screening: a powerful approach to systems cell biology and drug discovery
Title:
High content screening: a powerful approach to systems cell biology and drug discovery
Contributors:
Taylor, D. Lansing., Haskins, Jeffrey R., Giuliano, Kenneth A.
Publisher Information:
Totowa, N.J. : Humana Press, c2007.
Publication Year:
2006
Physical Description:
xiii, 444 p. : ill. (some col.) ; 27 cm. +
Series:
Methods in molecular biology
Methods in molecular biology (Clifton, N.J.)
Methods in molecular biology (Clifton, N.J.)
Subject Terms:
Contents Note:
Past, present, and future of high content screening and the field of cellomics / D.L. Taylor -- A pharmaceutical company user's perspective on the potential of high content screening in drug discovery / A.F. Hoffman and R.J. Garippa -- Linking microscopy and high content screening in large-scale biomedical research / J.G. Evans and P. Matsudaira -- Requirements, features, and performance of high content screening platforms / A.H. Gough and P.A. Johnston -- Characteristics and value of directed algorithms in high content screening / R.N. Ghosh, O. Lapets and J.R. Haskins -- Characteristics and value of machine learning for imaging in high content screening / J.A. Klenk -- Tools for quantitative and validated measurements of cells / A.L. Plant [and others] -- Automated cell plating and sample treatments for fixed cells in high content assays / G.R. Richards [and others] --
Differentiating primary human cells in rapid-throughput discovery applications / D.R. Marshak and D.E. Greenwalt -- Use of the CellCard System for analyzing multiple cell types in parallel / O. Beske, D. Bassoni and S. Goldbard -- Reagents to measure and manipulate cell functions / K.A. Giuliano, D.L. Taylor and A.S. Waggoner -- Fluorescent proteins and engineered cell lines / N. Thomas -- Optimizing the integration of immunoreagents and fluorescent probes for multiplexed high content screening assays / K.A. Giuliano -- The HaloTag: a novel technology for cell imaging and protein analysis / G.V. Los and K. Wood -- Protein labeling with FlAsH and ReAsH / T. Machleidt, M. Robers and G.T. Hanson -- Exploiting network biology to improve drug discovery / M.L. MacDonald and J.K. Westwick -- Physiological indicators of cell function / M.J. Ignatius and J.T. Hung -- The use of siRNA to validate immunofluorescence studies / K.G. Moore, W. Speckmann and R.P. Herzig --
Caged substrates applied to high content screening: an introduction with an eye to the future / P.G. Conrad, 2nd, R.V. Chavli and R.S. Givens -- Overview of informatics for high content screening / R.T. Dunlay, W.J. Czekalski and M.A. Collins -- Large-scale data management for high content screening / L.S. Garfinkel -- An integrated biomedical knowledge extraction and analysis platform: using federated search and document clustering technology / D.P. Taylor -- Visualization of high content screening data / M.J. Anstett -- Pathway mapping tools for analysis of high content data / S. Ekins [and others] -- Systems biology in cancer research: genomics to cellomics / J.L. Stilwell [and others] -- Target validation in drug discovery / R.A. Blake -- High content screening as a screening tool in drug discovery / A. Nichols -- Discovery of protein kinase phosphatase inhibitors / A. Vogt and J.S. Lazo -- High content translocation assays for pathway profiling / F. Loechel [and others] --
In vitro cytotoxicity assessment / P. O'Brien and J.R. Haskins -- Neurite outgrowth in retinal ganglion cell culture / J.B. Kerrison and D.J. Zack.
Differentiating primary human cells in rapid-throughput discovery applications / D.R. Marshak and D.E. Greenwalt -- Use of the CellCard System for analyzing multiple cell types in parallel / O. Beske, D. Bassoni and S. Goldbard -- Reagents to measure and manipulate cell functions / K.A. Giuliano, D.L. Taylor and A.S. Waggoner -- Fluorescent proteins and engineered cell lines / N. Thomas -- Optimizing the integration of immunoreagents and fluorescent probes for multiplexed high content screening assays / K.A. Giuliano -- The HaloTag: a novel technology for cell imaging and protein analysis / G.V. Los and K. Wood -- Protein labeling with FlAsH and ReAsH / T. Machleidt, M. Robers and G.T. Hanson -- Exploiting network biology to improve drug discovery / M.L. MacDonald and J.K. Westwick -- Physiological indicators of cell function / M.J. Ignatius and J.T. Hung -- The use of siRNA to validate immunofluorescence studies / K.G. Moore, W. Speckmann and R.P. Herzig --
Caged substrates applied to high content screening: an introduction with an eye to the future / P.G. Conrad, 2nd, R.V. Chavli and R.S. Givens -- Overview of informatics for high content screening / R.T. Dunlay, W.J. Czekalski and M.A. Collins -- Large-scale data management for high content screening / L.S. Garfinkel -- An integrated biomedical knowledge extraction and analysis platform: using federated search and document clustering technology / D.P. Taylor -- Visualization of high content screening data / M.J. Anstett -- Pathway mapping tools for analysis of high content data / S. Ekins [and others] -- Systems biology in cancer research: genomics to cellomics / J.L. Stilwell [and others] -- Target validation in drug discovery / R.A. Blake -- High content screening as a screening tool in drug discovery / A. Nichols -- Discovery of protein kinase phosphatase inhibitors / A. Vogt and J.S. Lazo -- High content translocation assays for pathway profiling / F. Loechel [and others] --
In vitro cytotoxicity assessment / P. O'Brien and J.R. Haskins -- Neurite outgrowth in retinal ganglion cell culture / J.B. Kerrison and D.J. Zack.
Original Identifier:
ocm65195280
Document Type:
Book
Book
Language:
English
ISBN:
978-1-58829-731-0
1-58829-731-4
1-58829-731-4
Rights:
This record is part of the Harvard Library Bibliographic Dataset, which is provided by the Harvard Library under its Bibliographic Dataset Use Terms and includes data made available by, among others, OCLC Online Computer Library Center, Inc. and the Library of Congress.
Notes:
Includes bibliographical references and index.
Accession Number:
edshlc.010129783.1
Database:
Harvard Library Bibliographic Dataset