Treffer: Mercury toxicokinetics in Wistar rats exposed to elemental mercury vapour: modeling and computer simulation.

Title:
Mercury toxicokinetics in Wistar rats exposed to elemental mercury vapour: modeling and computer simulation.
Authors:
Falnoga I; Jozef Stefan Institute, University of Ljubljana, Slovenia., Mrhar A, Karba R, Stegnar P, Skreblin M, Tusek-Znidaric M
Source:
Archives of toxicology [Arch Toxicol] 1994; Vol. 68 (7), pp. 406-15.
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print Cited Medium: Print ISSN: 0340-5761 (Print) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Imprint Name(s):
Original Publication: Berlin, New York, Springer-Verlag.
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Substance Nomenclature:
FXS1BY2PGL (Mercury)
Entry Date(s):
Date Created: 19940101 Date Completed: 19941219 Latest Revision: 20190904
Update Code:
20250114
DOI:
10.1007/s002040050090
PMID:
7979956
Database:
MEDLINE

Weitere Informationen

The kinetics of total mercury (Hg) absorption, distribution and elimination in Wistar rats exposed for long periods to elemental mercury vapour (Hg zero) in the Idrija mercury mine were studied. From the experimental data base a compartmental model was built as a framework for experimental data interpretation and prediction of organ mercury levels under different conditions. Using the model the exposures of rats under conditions comparable to those of professionally exposed workers (mercury miners, workers in the chloralkali industry) and individuals with amalgam fillings were simulated.