Treffer: GermVersity: A free and user-friendly interface to enhance the visualization and analysis of genebank data.
Mol Plant. 2020 Aug 3;13(8):1194-1202. (PMID: 32585190)
Nat Methods. 2011 Sep 04;8(10):833-5. (PMID: 21892150)
Front Plant Sci. 2021 Jul 01;12:674036. (PMID: 34276731)
Plants (Basel). 2020 Jun 29;9(7):. (PMID: 32610615)
PLoS One. 2024 May 2;19(5):e0302158. (PMID: 38696404)
Plant Phenomics. 2019 Mar 26;2019:7507131. (PMID: 33313536)
Plants (Basel). 2020 Aug 18;9(8):. (PMID: 32824806)
Genomics Proteomics Bioinformatics. 2021 Aug;19(4):629-640. (PMID: 34492338)
Front Genet. 2019 Nov 22;10:954. (PMID: 31824551)
Science. 1908 Jul 10;28(706):49-50. (PMID: 17779291)
Front Plant Sci. 2017 Sep 12;8:1551. (PMID: 28955351)
Ecol Appl. 2011 Mar;21(2):335-42. (PMID: 21563566)
New Phytol. 2018 Mar;217(4):1407-1419. (PMID: 29359808)
Gigascience. 2019 Feb 1;8(2):. (PMID: 30535326)
Gigascience. 2015 Feb 25;4:7. (PMID: 25722852)
PLoS One. 2011 May 04;6(5):e19379. (PMID: 21573248)
Bioinformatics. 2007 Oct 1;23(19):2633-5. (PMID: 17586829)
Bioinformatics. 2019 Feb 1;35(3):526-528. (PMID: 30016406)
Nat Genet. 2019 Feb;51(2):200-201. (PMID: 30664746)
Mol Biol Evol. 1987 Jul;4(4):406-25. (PMID: 3447015)
Mol Biol Evol. 2013 Jul;30(7):1687-99. (PMID: 23543094)
Nat Rev Genet. 2005 Dec;6(12):946-53. (PMID: 16341075)
Nat Genet. 2010 Apr;42(4):348-54. (PMID: 20208533)
Am J Hum Genet. 2011 Jan 7;88(1):76-82. (PMID: 21167468)
New Phytol. 2016 Apr;210(2):589-601. (PMID: 26777878)
Bioinformatics. 2012 Sep 15;28(18):2397-9. (PMID: 22796960)
PLoS Genet. 2006 Dec;2(12):e190. (PMID: 17194218)
BMC Genet. 2010 Oct 15;11:94. (PMID: 20950446)
Nat Commun. 2021 Jan 29;12(1):702. (PMID: 33514713)
Database (Oxford). 2015 May 07;2015:bav021. (PMID: 25953079)
PLoS Genet. 2016 Feb 01;12(2):e1005767. (PMID: 26828793)
Plants (Basel). 2021 Jan 28;10(2):. (PMID: 33525314)
Evolution. 1984 Nov;38(6):1358-1370. (PMID: 28563791)
PeerJ. 2017 Dec 5;5:e4095. (PMID: 29230356)
Plant Sci. 2019 May;282:60-72. (PMID: 31003612)
Nat Genet. 2010 Apr;42(4):355-60. (PMID: 20208535)
Front Plant Sci. 2018 May 08;9:609. (PMID: 29868066)
Front Genet. 2022 Aug 05;13:910386. (PMID: 35991553)
Weitere Informationen
Genebanks are crucial for food security and industrial applications. However, their heterogeneous nature hinders effective utilization. To address this, the GermVersity platform was developed to integrate conventional, artificial intelligence, and data science approaches to the transversal analysis of data associated with genebank accessions. GermVersity aids in the classification and prioritization of germplasm diversity, facilitating the conservation and utilization of valuable genetic resources in agriculture. The GermVersity proposal is focused on developing a user-friendly application to visualize, analyze and interpret analysis-ready data from genebanks. The application's case study uses data from the bean genebank at Bioversity International - CIAT but can be adapted for other genebanks and broader collections. GermVersity is divided into three modules. The first module analyzes genetic diversity using phenotypic and SNP data. In this module users can prioritize morphological descriptors for efficient classification of accessions, define genetic clusters or populations, calculate basic diversity statistics per locus and per population, and estimate genetic divergence among clusters or populations. The second module implements spatial distribution modeling, allowing users to understand ecological diversity across the geographical distribution range of a set of accessions. The third module characterizes the genomic architecture of phenotypic trait variation and adaptation to ecological niches using genome-wide association implemented in prediction integrated tools (GAPIT) and Latent Factor Mixed Model (LFMM) analysis. The GermVersity platform was built using Shiny-Golem and is hosted on GitHub for free use. To access it, users can install the library and run the application through specific commands in R. Responsible use of algorithms is recommended, along with the inspection of results for biological coherence. Ultimately, GermVersity offers an integrated analytical pipeline to leverage genebank diversity as part of pre-breeding efforts.
(Copyright: © 2026 Ramirez-Gil et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
The authors have declared that no competing interests exist.