• Virtual 3D surface imaging sys...

Treffer: Virtual 3D surface imaging system for the validation of tumor tracking algorithm used in surface-guided radiotherapy.

Title:
Virtual 3D surface imaging system for the validation of tumor tracking algorithm used in surface-guided radiotherapy.
Authors:
Wu X; School of Biomedical Engineering, Anhui Medical University, Hefei, China.; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China., Wei Z; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China., Zhai S; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China., Zhang Y; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China., Liu Z; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China., Jiang T; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China., Zhang L; Information Materials and Intelligent Sensing Laboratory of Anhui Province, Anhui University, Hefei, P.R. China., Qian J; School of Biomedical Engineering, Anhui Medical University, Hefei, China.; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China.
Source:
Journal of applied clinical medical physics [J Appl Clin Med Phys] 2025 Nov; Vol. 26 (11), pp. e70290.
Publication Type:
Journal Article; Validation Study
Language:
English
Journal Info:
Publisher: Wiley on behalf of American Association of Physicists in Medicine Country of Publication: United States NLM ID: 101089176 Publication Model: Print Cited Medium: Internet ISSN: 1526-9914 (Electronic) Linking ISSN: 15269914 NLM ISO Abbreviation: J Appl Clin Med Phys Subsets: MEDLINE
Imprint Name(s):
Publication: 2017- : Malden, MA : Wiley on behalf of American Association of Physicists in Medicine
Original Publication: Reston, VA : American College of Medical Physics, c2000-
MeSH Terms:
Algorithms* , Radiotherapy, Image-Guided*/methods , Imaging, Three-Dimensional*/methods , Radiotherapy Planning, Computer-Assisted*/methods , Neoplasms*/radiotherapy , Neoplasms*/diagnostic imaging , Phantoms, Imaging* , Image Processing, Computer-Assisted*/methods, Humans ; Radiotherapy Dosage ; Tomography, X-Ray Computed/methods ; Computer Simulation ; Radiotherapy, Intensity-Modulated/methods
References:
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Grant Information:
U1932158 National Natural Science Foundation of China; 81871085 National Natural Science Foundation of China; 82271519 National Natural Science Foundation of China; ZR2019LZL018 Natural Science Foundation of Shandong Province; 2208085J10 Anhui Province Funds for Distinguished Young Scientists; 2019HSC-CIP003 Collaborative Innovation Program of Hefei Science Center, CAS; 2019M652403 China Postdoctoral Science Foundation; 202002048 Project of Postdoctoral Innovation of Shandong Province
Contributed Indexing:
Keywords: phase measurement profilometry; surface imaging; surface‐guided radiotherapy; unity; virtual simulation
Entry Date(s):
Date Created: 20251107 Date Completed: 20251107 Latest Revision: 20251110
Update Code:
20251110
PubMed Central ID:
PMC12593527
DOI:
10.1002/acm2.70290
PMID:
41201185
Database:
MEDLINE

Weitere Informationen

Purpose: To develop a surface 3D reconstruction simulation system based on the Phase Measurement Profilometry (PMP) and the Unity physics engine and validate its feasibility for assisting in the development of the Surface-Guided Radiotherapy (SGRT) tumor tracking algorithm.
Methods: The components, such as cameras and projectors, are set up in the Unity environment to enable structured-light-based surface 3D reconstruction simulation using the PMP. This process includes structured light projection, camera calibration, phase unwrapping, and point cloud reconstruction procedures. The influence of parameter settings on the effectiveness of 3D reconstruction is investigated, including different distances and angles between the camera and the measurement surface, as well as variations in light intensity. The simulation capabilities of the system are validated by comparing surface imaging of the same human torso model in a radiotherapy room environment and within the simulation system. Additionally, the simulation system is further utilized to acquire surface imaging data required for the SGRT tumor tracking algorithm. A comparison is made between this data and the idealized skin surface imaging data obtained directly from CT reconstruction segmentation to verify the system's supportive role in the development of the SGRT tumor tracking algorithm.
Results: The effects of varying light intensity and object positioning in the simulation system are consistent with those reported in previous studies conducted in real-world environments. The root mean square errors (RMSE) of the surface imaging point clouds from different perspectives between the simulation system and the actual environment are 0.46, 0.47, and 0.52 mm, all at sub-millimeter levels. The validation in the development of the SGRT tumor tracking algorithm indicates that the simulation system enables the SGRT algorithm development to avoid relying on overly idealized surface imaging data.
Conclusions: The simulation system based on PMP and Unity has been proposed, enabling a broader range of measurement conditions to be set in the virtual environment, thereby saving costs for measurements in real-world scenarios. This system can also be utilized to assist in the validation of the SGRT tumor tracking algorithms, thereby advancing progress in this field.
(© 2025 The Author(s). Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine.)