Treffer: Biocompatible composites based on alginate, polycaprolactone, and nanocellulose - A review.

Title:
Biocompatible composites based on alginate, polycaprolactone, and nanocellulose - A review.
Authors:
Ikhtiarini N; Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia., Kamil MZ; Department of Chemistry, Faculty of Science and Mathematics, Universitas Indonesia, Depok, West Java 16424, Indonesia., Bukit BF; Faculty of Science and Technology, Universitas Quality Berastagi, North Sumatera 22152, Indonesia., Juliadmi D; Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia., Prasetiyo KW; Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia., Fransiska D; Research Center for Marine and Land Bioindustry, National Research and Innovation Agency (BRIN), Lombok 83352, Indonesia., Sedayu BB; Research Center for Food Technology and Processing, National Research and Innovation Agency (BRIN), Yogyakarta 55861, Indonesia., Subiyanto B; Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia., Sulastiningsih IM; Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia., Rochima E; Department of Fishery, Faculty of Fisheries and Marine Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia; Research Collaboration Center for Marine Biomaterials, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia., Arivendan A; International Joint Laboratory on Human-Centric Intelligence and Systems, Shien-Ming Wu School of Intelligent Engineering, South China University of Technology, Xingye Ave, Guangzhou 511442, Guangdong, China., Syamani FA; Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia; Research Collaboration Center for Marine Biomaterials, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia. Electronic address: fird003@brin.go.id.
Source:
International journal of biological macromolecules [Int J Biol Macromol] 2025 Jun; Vol. 311 (Pt 1), pp. 143423. Date of Electronic Publication: 2025 Apr 22.
Publication Type:
Journal Article; Review
Language:
English
Journal Info:
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Imprint Name(s):
Publication: Amsterdam : Elsevier
Original Publication: Guildford, Eng., IPC Science and Technology Press.
MeSH Terms:
Alginates*/chemistry , Cellulose*/chemistry , Polyesters*/chemistry , Biocompatible Materials*/chemistry , Nanocomposites*/chemistry, Humans ; Tissue Engineering ; Tissue Scaffolds/chemistry
Contributed Indexing:
Keywords: Alginate; Applications; Biocompatibility; Composite; Nanocellulose; Polycaprolactone; Synthesis-method
Substance Nomenclature:
0 (Alginates)
9004-34-6 (Cellulose)
24980-41-4 (polycaprolactone)
0 (Polyesters)
0 (Biocompatible Materials)
Entry Date(s):
Date Created: 20250424 Date Completed: 20250525 Latest Revision: 20250525
Update Code:
20250526
DOI:
10.1016/j.ijbiomac.2025.143423
PMID:
40274166
Database:
MEDLINE

Weitere Informationen

Biocompatible composite materials are gaining attention for biomedical applications due to their biodegradability, mechanical strength, and tunability. The fabrication techniques and applications significantly impact composite performance. This paper explores the synthesis of composites from alginate, polycaprolactone (PCL), and nanocellulose, emphasizing their distinct properties for biomedical use. Alginate provides excellent biocompatibility and gelling ability, PCL offers controlled mechanical strength, and nanocellulose enhances stability due to its superior mechanical properties. Key fabrication techniques include solution mixing, hot pressing, melt mixing/extrusion, electrospinning, and 3D printing, each influencing structural integrity, mechanical properties, and material dispersion. Optimizing fabrication methods is crucial for achieve desirable properties in specific applications. The choice of synthesis technique directly affects the final use, such as drug delivery systems, tissue engineering scaffolds, or wound dressings. This review discusses the challenges and prospects of developing alginate-, PCL-, and nanocellulose-based composites, offering insights into their future biomedical applications.
(Copyright © 2025. Published by Elsevier B.V.)

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Firda Aulya Syamani reports financial support was provided by Research Organization for Nanotechnology and Materials, National Research and Innovation Agency (BRIN). If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.