Treffer: Development of an automatic program for the stereological estimation of the volume weighted mean volume of cell nuclei.

Title:
Development of an automatic program for the stereological estimation of the volume weighted mean volume of cell nuclei.
Authors:
Masson E; LEI-ISMRa, Caen, France., Herlin P, Bloyet D, Duigou F, Mandard AM
Source:
Pathology, research and practice [Pathol Res Pract] 1992 Jun; Vol. 188 (4-5), pp. 438-42.
Publication Type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Language:
English
Journal Info:
Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print Cited Medium: Print ISSN: 0344-0338 (Print) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE
Imprint Name(s):
Publication: Stuttgart : Gustav Fischer Verlag
Original Publication: Stuttgart, New York, Fischer.
MeSH Terms:
Software*, Cell Nucleus/*ultrastructure , Image Processing, Computer-Assisted/*methods, Epithelium/pathology ; Epithelium/ultrastructure ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/ultrastructure ; Humans ; Melanoma/pathology ; Melanoma/ultrastructure ; Prognosis ; Reproducibility of Results ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/ultrastructure
Entry Date(s):
Date Created: 19920601 Date Completed: 19921112 Latest Revision: 20061115
Update Code:
20250114
DOI:
10.1016/S0344-0338(11)80034-8
PMID:
1409068
Database:
MEDLINE

Weitere Informationen

A stereological method was recently developed for the estimation of the volume weighted mean volume of particles from 2D sections. Several authors successfully applied this manual method to paraffin sections of bladder cancers and malignant melanomas and found a good correlation between the mean nuclear volume and the histological grading and prognosis of these tumors. The implementation of this measuring method on an automatic image analyser, devoted to routine work in tumor pathology, is presented. The accuracy of the automatic measurement has been evaluated together with the first results obtained from human esophageal cancers.