Result: AUDIT: An open-source Python library for AI model evaluation with use cases in MRI brain tumor segmentation.

The development of artificial intelligence (AI) models for medical image analysis remains a significant challenge. Main issues include a lack of model generalization, the need for extensive datasets for training, and poor model robustness for clinical application. Current evaluation frameworks often fail to provide subject-based insights necessary to identify model biases and address domain shifts. To address these limitations, this study introduces AUDIT, an open-source Python library designed to enhance the evaluation of segmentation models and the analysis of MRI datasets. AUDIT includes modules for extracting region-specific features and calculating performance metrics, as well as a dynamic web APP for interactive model evaluation and data exploration. All the source code, tutorials, and documentation can be found at https://github.com/caumente/AUDIT , and can directly be installed from the Python Package Index using pip install auditapp. Through a series of use cases commonly encountered in AI-driven brain tumor segmentation, this manuscript highlights the versatility and broad applicability of the AUDIT library across diverse scenarios. AUDIT was designed to fill the existing gaps in the literature on the evaluation of AI segmentation models, ultimately aiming to advance the AI medical image analysis domain. Beyond its extensive analysis capabilities, AUDIT has been designed to support integration with external libraries and applications. • Open-source Python library for evaluating medical image segmentation models and analyzing MRI datasets. • Modular design inspired by modern deep learning frameworks to support integration with external libraries. • Extracts multiple features, including statistical, textural, spatial, and tumor-specific characteristics. • Includes an interactive web application for dynamic data exploration and visualization. • Supports statistical testing, longitudinal analysis, and subject-level bias analysis. [ABSTRACT FROM AUTHOR]